Ganaxolone for the treatment of patients 2 years of age and older with seizures caused by CDKL5 deficiency disorder

12 February 2025 - NICE has published final evidence-based recommendations on the use of ganaxolone (Ztalmy) for the treatment of ...

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Nivolumab and ipilimumab for the first-line treatment of patients with metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency

10 February 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Pembrolizumab for adjuvant treatment of patients with resected non-small-cell lung cancer (final guidance)

5 February 2025 - NICE has published final evidence-based recommendations on the use of pembrolizumab (Keytruda) for the adjuvant treatment ...

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Elacestrant dihydrochloride for the treatment of patients with advanced, oestrogen receptor positive, HER2 negative breast cancer with an ESR1 mutation after endocrine treatment (final guidance)

5 February 2025 - Evidence-based recommendations on elacestrant (Korserdu) for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation ...

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Durvalumab with tremelimumab for the first-line treatment of patients with advanced or unresectable hepatocellular carcinoma

4 February 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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The use of real world data for estimating relative treatment effects in NICE health technology assessment submissions: a review

1 February 2025 - This paper investigates the current use of real world data for estimating relative treatment effects in NICE ...

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Groundbreaking one-off gene therapy approved for severe sickle cell disease

31 January 2025 - People in England with severe sickle cell disease will be among the first to receive treatment using ...

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Vertex announces Casgevy reimbursement agreement for the treatment of sickle cell disease in England

31 January 2025 - Agreement means eligible sickle cell disease patients in England now have access to Casgevy. ...

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Thousands of people with a severe dust mite allergy are set to benefit from life-changing treatment

30 January 2025 - We've recommended an innovative daily tablet treatment shown to reduce symptoms and improve quality of life. ...

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Spesolimab for the treatment of patients with generalised pustular psoriasis flares

24 January 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Harnessing expertise to improve patient access to innovative health technologies

28 January 2025 - Introducing the Medicines and Medical Devices Access Initiative: a new collaboration that aims to improve patient access ...

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Tarlatamab for previously treated patients with advanced small-cell lung cancer

28 January 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Vadadustat for the treatment of adults with symptomatic anaemia on dialysis for chronic kidney disease

23 January 2025 - NICE has published final evidence-based recommendations on the use of vadadustat (Vafseo) for the treatment of ...

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Abiraterone acetate with niraparib tosylate monohydrate and prednisone for untreated hormone-relapsed metastatic prostate cancer

22 January 2025 - NICE is unable to make a recommendation on the use in the NHS of abiraterone acetate with ...

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NICE has made six times more lung cancer treatment recommendations over the past ten years than in the previous decade

21 January 2025 - We have also recommended osimertinib for routine use on the NHS today. ...

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