Use of surrogate endpoints in health technology assessment: a review of selected NICE technology appraisals in oncology

19 February 2025 - Surrogate endpoints, used to substitute for and predict final clinical outcomes, are increasingly being used to support ...

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Selpercatinib for the treatment of patients with advanced RET fusion positive non-small-cell lung cancer

19 February 2025 - NICE has published final evidence-based recommendations on the use of selpercatinib (Retsevmo) for the treatment of ...

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Durvalumab in combination with etoposide phosphate and either carboplatin or cisplatin for the first-line treatment of patients with extensive-stage small-cell lung cancer

19 February 2025 - NICE has published final evidence-based recommendations on the use of durvalumab (Imfinzi) in combination with etoposide ...

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Selpercatinib for the treatment of patients with advanced thyroid cancer with a RET alteration untreated with a targeted cancer medicine

12 February 2025 - NICE has published final evidence-based recommendations on the use of selpercatinib (Retsevmo) for the treatment of ...

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Selpercatinib for the treatment of patients with advanced thyroid cancer with a RET alteration after treatment with a targeted cancer medicine (final guidance)

12 February 2025 - NICE has published final evidence-based recommendations on the use of selpercatinib (Retsevmo) for the treatment of ...

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Nivolumab and ipilimumab for the first-line treatment of patients with metastatic colorectal cancer with high microsatellite instability or mismatch repair deficiency

10 February 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Pembrolizumab for adjuvant treatment of patients with resected non-small-cell lung cancer (final guidance)

5 February 2025 - NICE has published final evidence-based recommendations on the use of pembrolizumab (Keytruda) for the adjuvant treatment ...

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Elacestrant dihydrochloride for the treatment of patients with advanced, oestrogen receptor positive, HER2 negative breast cancer with an ESR1 mutation after endocrine treatment (final guidance)

5 February 2025 - Evidence-based recommendations on elacestrant (Korserdu) for treating oestrogen receptor-positive HER2-negative advanced breast cancer with an ESR1 mutation ...

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Durvalumab with tremelimumab for the first-line treatment of patients with advanced or unresectable hepatocellular carcinoma

4 February 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Abiraterone acetate with niraparib tosylate monohydrate and prednisone for untreated hormone-relapsed metastatic prostate cancer

22 January 2025 - NICE is unable to make a recommendation on the use in the NHS of abiraterone acetate with ...

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NICE has made six times more lung cancer treatment recommendations over the past ten years than in the previous decade

21 January 2025 - We have also recommended osimertinib for routine use on the NHS today. ...

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Capivasertib in combination with fulvestrant for the treatment of patients with advanced, hormone receptor positive, HER2 negative breast cancer after endocrine treatment

14 January 2025 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Erdafitinib for the treatment of patients with metastatic or unresectable FGFR altered urothelial cancer

9 January 2024 - The Department of Health and Social Care has asked NICE to produce guidance on the use ...

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Over 1,000 people with advanced breast cancer set to benefit from new once a day tablet

19 December 2024 - We’ve issued final draft guidance recommending a new once a day tablet that is set to benefit ...

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Toripalimab in combination with chemotherapy for the first-line treatment of patients with advanced oesophageal squamous cell cancer

11 December 2024 - NICE is unable to make a recommendation on the use in the NHS of toripalimab (Loqtorzi) in ...

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