Unravelling the association between uncertainties in model-based economic analysis and funding recommendations of medicines in Australia

PharmacoEconomics

14 February 2025 - Health technology assessment is used extensively by the PBAC to inform medicine funding recommendations in Australia. 

The PBAC often does not recommend medicines due to uncertainties in economic modelling that result in delaying access to medicines for patients. The systematic identification of which uncertainties can be reduced with alternative evidence or the collection of additional data can help inform recommendations. 

This study aims to characterise different types of uncertainty in economic models and empirically assess their association with the PBAC recommendations.

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Michael Wonder

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Michael Wonder