Posted by Michael Wonder on 19 Sep 2022
Registry-based randomised trials: the best of both worlds?
15 September 2022 - IQWiG authors present the advantages and disadvantages of study designs that combine explanatory and pragmatic aspects. Registry-based randomised controlled trials in particular have potential.
Randomised controlled trials, such as those required for the approval of new drugs, are often criticised because they are too complex, too lengthy and - due to the heavily controlled study conditions - hardly transferrable to everyday clinical care.
