Johnson & Johnson seeks first icotrokinra US FDA approval aiming to revolutionise treatment paradigm for adults and adolescents with plaque psoriasis

Johnson & Johnson

21 July 2025 - Icotrokinra is a first in class investigational targeted oral peptide that selectively blocks the IL-23 receptor.

Johnson & Johnson today announced the submission of a new drug application to the US FDA seeking the first approval of icotrokinra, a first in class investigational targeted oral peptide that selectively blocks the IL-23 receptor for the treatment of adults and paediatric patients 12 years of age and older with moderate to severe plaque psoriasis.

Read Johnson & Johnson press release 

Michael Wonder

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Michael Wonder

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Medicine , US , Dossier