Jaypirca (pirtobrutinib), the first and only non-covalent (reversible) BTK inhibitor, now available in Canada for adult patients with relapsed or refractory mantle cell lymphoma and chronic lymphocytic leukaemia

Eli Lilly

27 January 2026 - The approval of Jaypirca marks Lilly Canada's first haematology launch in Canada.

Eli Lilly Canada announced today that Jaypirca (pirtobrutinib, 100 mg & 50 mg tablets) is now approved and available for use as monotherapy for the treatment of adult patients in Canada with:

  • Mantle cell lymphoma relapsed or refractory in patients who have previously received at least two lines of systemic therapy including a Bruton tyrosine kinase inhibitor
  • Chronic lymphocytic leukaemia/small lymphocytic lymphoma who have received at least two prior lines of therapy, including a BTK inhibitor and a BCL-2 inhibitor

Read Eli Lilly press release

Michael Wonder

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Michael Wonder

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Cancer , Medicine , Market access , Canada