Posted by Michael Wonder on 01 Sep 2016
Elotuzumab in multiple myeloma: additional clinical benefit is not proven
1 September 2016 - The only study available was unsuitable for the benefit assessment.
The monoclonal antibody elotuzumab has been approved in combination with lenalidomide and dexamethasone since May 2016 for further treatment of multiple myeloma in adults who have received at least one previous treatment. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether these patients benefit from this new combination.
Since the only study submitted by the drug manufacturer was unsuitable for answering this research question because the dosage of a comparator drug was too low, it was concluded that an added benefit of the new combination therapy in comparison with the appropriate comparator therapy is not proven.
