Baxfendy approved in the US as the first and only aldosterone synthase inhibitor treatment for adults with hypertension

AstraZeneca

18 May 2026 - Approval based on BaxHTN Phase 3 results showing statistically significant and clinically meaningful reduction in systolic blood pressure in patients with uncontrolled or resistant hypertension.

AstraZeneca’s Baxfendy (baxdrostat) has been approved in the US as a first in class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive medications, to lower blood pressure in adults who are not adequately controlled.

Read AstraZeneca press release

Michael Wonder

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Michael Wonder

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Outcome , Medicine , US , Registration